Stuck in a small Appalachian town, a young woman’s only escape from the daily grind is playing advanced video games. She is such a good player that a company sends her a new video game system to test…but it has a surprise in store. It unlocks all of her dreams of finding a purpose, romance, and glamour in what seems like a game…but it also puts her and her family in real danger.

After he and his wife are murdered, marine Ray Garrison is resurrected by a team of scientists. Enhanced with nanotechnology, he becomes a superhuman, biotech killing machine - Bloodshot. As Ray first trains with fellow super-soldiers, he cannot recall anything from his former life. But when his memories flood back and he remembers the man that killed both him and his wife, he breaks out of the facility to get revenge, only to discover that there's more to the conspiracy than he thought.