A full moon rises in Beacon Hills, and with it a terrifying evil has emerged. The wolves are howling once again, calling for the return of Banshees, Werecoyotes, Hellhounds, Kitsunes, and every other shapeshifter in the night. But only a Werewolf like Scott McCall, no longer a teenager yet still an Alpha, can gather both new allies and reunite trusted friends to fight back against what could be the most powerful and deadliest enemy they’ve ever faced.

A frantic call to the CDC has everyone paranoid, especially since it was designed to target werewolves. Scott, Malia and Kira lock themselves in the Hale vault, unaware of their salvation within their grasp.