A middle-class boy in Ahmedabad, Satyaprem falling in one-sided love with Katha, who is coping with her breakup with Tapan. Through the journey, they discover each other's life and complement in accomplishing what was left halfway.

After ending the season 1 of “Samantar” where Kumar Mahajan finds out from the diary that a new woman is going to enter his life we take the story further with season 2 of Samantar. Kumar’s quest with his destiny continues and in spite his best efforts to alter his destiny the mysterious woman enters into his life. Who is this woman and will Kumar face the same fate as mentioned by Chakrapani in his diary or will he be able to re-write his own future, forms the crux of the story.

Anandibai Joshi, the First Indian woman who went against all odds to get herself educated and became a doctor to set an example and inspired generations to come. In times, when gender equality and feminism are raised at almost every forum and podium, a couple in the 1800's practiced and fought for these very ideas. Anandi Gopal is a love story more than a biopic about the struggle of a husband to teach his wife and her response and determination to become the first Indian Female Doctor.