Mukherjee Dar Bou is a story based on a modern dysfunctional family revolving around the complex and intricate yet caring relationship of a mother-in-law and daughter-in-law. The story revolves around a Bengali home maker whose name is not known till the end of the film, and who is mostly referred as "Mukherjee Dar Bou". Mukherjee Dar Bou (Aditi) is married for more than ten years and has a daughter of six years old . Aditi's married life was usual but it takes a turn when her father-in-law passes away.

A dark comedic take on the 2011 hooch fatalities in Bengal, India. Here the local liquor, `Cholai' is a flourishing business, due to it's low price and addictive quality. A sudden turn of events is triggered when a batch of Cholai becomes toxic.