In the year 2020, when the entire world was reeling under the effect of corona virus, the deadly virus had created havoc all around. Slowly after months of suffering, doctors and scientist invented the vaccination for it. Now though the people were saved but people were still facing the dangers posed by floods earthquakes cyclone and asteroids. It seemed as if God was enjoying the suffering that had surrounded Earth. In this scenario a strange story begins scientists discovered one medicine called Amar Goli, by taking that medicine death rate declined. But when Yamraj sees that people are not dying, he decides to visit the earth and explain how the inventions of scientist can destroy the ecological balance of nature.

Nanu Ki Jaanu is a dark comedy, the story of which revolves around a Delhi land mafia agent (Abhay Deol) who tries to deal with the arrival of a ghost in his apartment.